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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKA
All Species:
23.64
Human Site:
S683
Identified Species:
47.27
UniProt:
P23743
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23743
NP_001336.2
735
82630
S683
G
R
R
L
A
K
C
S
E
I
T
F
H
T
T
Chimpanzee
Pan troglodytes
XP_001169813
623
69890
E572
R
R
L
A
K
C
S
E
I
T
F
H
T
T
K
Rhesus Macaque
Macaca mulatta
XP_001112326
735
82508
S683
G
R
R
L
A
K
C
S
E
I
T
F
H
T
T
Dog
Lupus familis
XP_531626
735
82556
S683
G
R
R
L
A
K
C
S
E
I
T
F
H
T
T
Cat
Felis silvestris
Mouse
Mus musculus
O88673
730
82744
S678
G
H
R
L
A
K
C
S
E
I
T
F
Q
T
T
Rat
Rattus norvegicus
P51556
727
82180
S675
G
H
R
L
A
K
C
S
E
I
T
F
Q
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235516
802
90547
S742
G
R
R
L
A
Q
C
S
S
V
V
I
R
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038780
727
81728
A676
L
K
S
A
V
R
L
A
K
T
S
Q
I
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
S1157
G
R
R
L
A
Q
C
S
E
V
I
I
K
T
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
P753
P
M
Q
I
D
G
E
P
W
M
Q
P
P
C
I
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
L1162
K
L
L
E
V
V
G
L
E
G
S
L
H
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
L672
W
N
Q
Q
P
C
T
L
T
I
S
H
H
G
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
98.9
92.9
N.A.
82.3
82.7
N.A.
N.A.
57.2
N.A.
62
N.A.
34.7
N.A.
46.1
35.3
Protein Similarity:
100
84.6
99.3
97
N.A.
88.9
88.9
N.A.
N.A.
70
N.A.
74.5
N.A.
44.9
N.A.
62.1
45.1
P-Site Identity:
100
13.3
100
100
N.A.
86.6
86.6
N.A.
N.A.
53.3
N.A.
6.6
N.A.
60
N.A.
0
13.3
P-Site Similarity:
100
13.3
100
100
N.A.
86.6
86.6
N.A.
N.A.
73.3
N.A.
40
N.A.
73.3
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
59
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
17
59
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
9
9
59
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
42
0
0
0
% F
% Gly:
59
0
0
0
0
9
9
0
0
9
0
0
0
9
9
% G
% His:
0
17
0
0
0
0
0
0
0
0
0
17
42
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
9
50
9
17
9
0
17
% I
% Lys:
9
9
0
0
9
42
0
0
9
0
0
0
9
0
17
% K
% Leu:
9
9
17
59
0
0
9
17
0
0
0
9
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
9
0
0
9
0
0
0
9
9
0
0
% P
% Gln:
0
0
17
9
0
17
0
0
0
0
9
9
17
0
9
% Q
% Arg:
9
50
59
0
0
9
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
0
9
0
0
0
9
59
9
0
25
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
9
0
9
17
42
0
9
75
42
% T
% Val:
0
0
0
0
17
9
0
0
0
17
9
0
0
9
0
% V
% Trp:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _